As shown in Table 4, our results indicate that our approach significantly outperforms MALLET and the baseline model in terms of both precision and average recall. To identify forum posts related to opioid commodity promotion and review, our methodology was designed to filter forum posts with opioid keywords and then use a classifier to the posts with the topics of interest. The classifier was built upon transfer learning and a crafted objective function that heavily weighs the penalty of misclassifying a positive instance. Our goal here was to identify anonymous forum posts with the topics of opioid commodity promotion (eg, listing promotion) and review (eg, report fake opioid vendors). We then analyzed these forum posts to profile underground opioid trading behaviors.

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Among them, suboxone and subutex medicines are most frequently mentioned by 2917 times in listings and traces in 10 platforms, followed by roxy series (ie, roxy, roxi, roxies, and roxys) with 2022 times and Lean with 1256 times. Both K9 and M30 were mostly found in Darkbay, within 384 listings in the year 2020, whereas Lean appeared 141 times in Empire listings. As a pioneer in organoid technology, HUB offers transformative solutions to the pharmaceutical industry for more effective, faster, and ethical drug development.

Sri Lanka Pancreatic And Bile Duct Cancer Market data and reports

From our measurement, we concluded that anonymous online marketplaces and forums provided easy-access platforms for global opioid supply. This paper seeks to complement current studies widening the understanding of opioid supply chains in underground marketplaces using comprehensive, large-scale, longitudinal anonymous marketplace and forum data. To this end, we propose a series of techniques to collect data; identify opioid jargon terms used in the anonymous marketplaces and forums; and profile the opioid commodities, suppliers, and transactions. Specifically, we first conducted a whole-site crawl of anonymous online marketplaces and forums to solicit data. Subsequently, we conducted a comprehensive, large-scale, longitudinal study to demystify opioid trading activities in anonymous markets and forums. In total, we collected 248,359 listings from 10 anonymous online marketplaces and 1,138,961 traces (ie, threads of posts) from 6 underground forums.

Drugs on the Menu: Greek Souvlaki Shop Exposed as Narcotics Hub

Ourexperienced moderation team reviews all cases within 3-7 days, ensuring fairresolution based on evidence and platform policies. Drughub Market maintains strict vendor verification to ensure marketplacequality and customer satisfaction. Drughub Market employs state-of-the-art security measures to protect yourprivacy and transactions. Paste the mirror URL in Tor browser, complete CAPTCHA verification, andcreate your secure account. If canary is not updated or signature fails verification, assume compromise. Admin key is used for signing official announcements, canary files, and critical security notices.

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This is the only official marketplace URL—any other address claiming to be Drug Hub is a phishing attempt. In this way, we collected 7100 promotion posts and 6408 review posts from forum posts in total. Recovered from the scene were nearly five kilograms of high-grade marijuana or “Kush” valued at P5.86 million, and over 1.5 kilograms of shabu worth around P17.3 million.

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• Latin America offers emerging growth potential through infrastructure expansion and rising industrial activity, while the Middle East & Africa benefits from growing investments in energy, construction, and smart infrastructure projects.
• If found guilty of these charges, Wilson faces a maximum penalty under federal law of life imprisonment, followed by a term of supervised release.
• The final sentence will be determined by a judge, taking into consideration applicable federal sentencing statutes and the Federal Sentencing Guidelines.
• Stay informed about the latest darknet marketplaces, secure browsing practices, and privacy tools.
• Welcome to The Global Filipino Magazine, your premier source of news, stories, and insights that connect the vibrant Filipino community in Dubai, the United Arab Emirates, and beyond.
• HARRISBURG, PA – A 25-year-old Shippensburg, Pennsylvania, resident has been indicted by a federal grand jury on six counts of drug trafficking, according to the United States Attorney’s Office for the Middle District of Pennsylvania.

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Additionally, DrugHub provides vendors with access to private mirrors, adding an extra layer of security against unauthorized access. Note that data for 2020 only included data from January to March; price per gram is in US $. Each year, Frost & Sullivan presents this award to the company that has developed a product with innovative features and functionality that is gaining rapid acceptance in the market. The award recognizes the quality of the solution and the customer value enhancements it enables. M&A activities help companies expand capabilities, market reach, and competitive positioning.

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In case of marketplace downtime or critical issues preventing normal support access, check this clearnet website for announcements. We will post updates regarding extended downtime, security incidents, or migration notices. The official Drug Hub marketplace is only accessible through the Tor network.

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• In early 2025, the company broke ground on a $2 billion manufacturing facility project in Wilson.
• HUB Organoids (HUB) is the global leader in the field of adult stem cell-derived organoids.
• As the number one market today, we pride ourselves onour advanced escrow protection androbust security systems, ensuring every transaction remains safe and secure.
• Market players are increasingly focusing on local collaborations and clinical research to enhance treatment options tailored to regional patient needs.
• Access Drughub market onion links or official Drughub mirrors to get started today.
• With a proven team and billions of dollars in transactions DrugHubmarket can be used with the confidence that your data is fully protected.

A steering committee made up of senior executives from both organizations will oversee the execution of the new development hub. The partnership aims to discover and develop new therapeutics, while also forging collaborations with academic and research institutions in the UAE and internationally, supporting Abu Dhabi’s broader ambitions in the life sciences sector. The Pancreatic And Bile Duct Cancer Drug Market refers to the global industry involved in the development, production, and deployment of Pancreatic And Bile Duct Cancer Drug solutions across various end-use sectors. You’re a small-time drug dealer in a fresh town with no cash, no product and no connections.

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We pride ourselves on relationships that have lasted generations because they are built on trust and transparency, but we aren’t satisfied to rest on past success. We define ourselves by the service we provide, the solutions we bring to your pharmacy and the trust you place in us. Administered by seasoned experts, pen-tested by top security specialists,with industry-leading protections like END GAME DDoS filter. Funds are automatically transferred to our secure escrow system, protectingboth buyer and vendor interests. Secure escrow system holds funds for 7-21 days depending on productcategory, with automatic release upon delivery confirmation or disputeresolution through our moderation team. All communications and sensitive data are protected using Pretty GoodPrivacy (PGP) encryption with 4096-bit keys, ensuring complete privacy fromthird-party interception.

Private mirrors are displayed in your account dashboard after qualification. Welcome to The Global Filipino Magazine, your premier source of news, stories, and insights that connect the vibrant Filipino community in Dubai, the United Arab Emirates, and beyond. “The entry and evidence recovery revealed a covert drug operation camouflaged under the guise of routine delivery services,” the agency reported. First Logevity Limited provides a service to strictly match groups or individuals seeking investment capital with individuals looking to invest. First Longevity Limited does not give advice on the risks of investment and is not authorised to carry out investment business under the Financial Services and Markets Act 2000 (“FSMA”). Digital transformation increases efficiency, data-driven decision-making, and adoption of advanced solutions.

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Increasing awareness campaigns and government support for cancer management initiatives are key contributors. The expanding pharmaceutical sector and international partnerships are facilitating access to innovative therapies. Challenges such as limited healthcare resources are being addressed through policy reforms and investments in diagnostic facilities. The focus on expanding treatment options and clinical research is expected to accelerate market growth, making Pakistan an emerging hub for pancreatic and bile duct cancer therapeutics in the region. Sri Lanka’s pancreatic and bile duct cancer drug market is expected to grow steadily, supported by increased healthcare spending and improved diagnostic capabilities. Rising awareness about cancer symptoms and early detection programs are crucial factors.

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• Efforts to improve diagnostic infrastructure and expand access to modern therapeutics are key growth factors.
• As time passed, the men from Delta Force adopted a mercenary attitude about military service, which accounted in part for their ever-worsening behavior.
• Manufacturers participating in Medicaid agree to provide outpatient drugs to covered entities at significantly reduced prices.
• M&A activities help companies expand capabilities, market reach, and competitive positioning.
• Nontraditional methods, as presented here by studying the online supply chain, present a novel approach for governmental and other large-scale solutions.
• The facility is also significant because it will manufacture Lilly’s highly-anticipated oral GLP-1, which is expected to receive approval in March.
• If canary is not updated or signature fails verification, assume compromise.

We then identified 311 opioid keywords and jargons to recognize 28,106 listings and 13,508 forum traces related to underground opioid trading activities. Finally, we used natural language processing techniques to extract opioid trading information to characterize underground opioid commodities, suppliers, and transactions. We aimed to profile the opioid supply chain in anonymous markets and forums via a large-scale, longitudinal measurement study on anonymous market listings and posts. Toward this, we propose a series of techniques to collect data; identify opioid jargon terms used in the anonymous marketplaces and forums; and profile the opioid commodities, suppliers, and transactions. We trained the semantic comparison model using the traces of Reddit as the benign corpora and the traces of the anonymous marketplaces/forums as the underground corpora.

In addition, we set parameters such as sleeping time to limit the speed of crawling. New vendors without an existing darknet marketplace history can join Drughub Market by paying a $1000 securitydeposit. This deposit reinforces trust on the Drughub darknet, ensures a commitment to high-qualityservice, and acts as insurance against potential disputes. Access Drughub market onion links or official Drughub mirrors to get started today. Our modification of the semantic comparison model will generate comparable word embeddings for opioid jargon words in legitimate documents (ie, benign corpora embedding) and in underground corpora (ie, underground corpora embedding).

Hence, we also gathered snapshots of 5 underground marketplaces and 6 forums collected by the anonymous marketplace archives programs and previous research projects [20]. We first conducted a whole-site crawl of anonymous online marketplaces and forums to solicit data. Anonymous online marketplaces and forums usually operate as hidden Tor services, which can only be resolved through Tor (an anonymity network). Figures 2 and 3 illustrate examples of opioid listings in The Versus Project and Alphabay.

Particularly, as shown in Table 8, the United States and the United Kingdom are always in the top 5 advertised origins among years. We compared our method with the state-of-the-art topic modeling method Machine Learning for Language Toolkit (MALLET) [30] and our model without transfer learning stage (baseline). In particular, MALLET is retrained and evaluated via 10-fold cross-validation. We also applied the MALLET topic modeling toolkit (package cc.mallet.topics MALLET’s class in JavaDoc API) on the same data set to predict the type of topic. The baseline model was applied directly to the labeled data (Table 3) and evaluated using 10-fold cross-validation. We used the metrics of precision and recall to compare the performance of different topic modeling methods.

The results show that vendors’ trustworthiness is a better predictor of vendor selection than product diversity or affordability. Considering social media data (eg, Twitter and Instagram), Nasralah et al [14] proposed a text mining framework to collect opioid data from social media and analyzed the most discussed topics to profile the opioid epidemic and crisis. Mackey et al [13] collected tweets related to the opioid topic to identify illicit online pharmacies and study the illegal sale of opioids in online marketing. Cherian et al [12] gathered codeine misuse data from Instagram posts to understand how misuse is happening and its misused form. To the best of our knowledge, a comprehensive overview of the opioid supply chain in the anonymous online marketplaces and forums, as well as a measurement study of trading activities, is still an open research challenge. This is the first study to measure and characterize opioid trading in anonymous online marketplaces and forums.

A hurricane came through our area, our rep actually delivered our order in his vehicle when delivery trucks couldn’t get through. He made sure that all of his stores had what they needed to stay open and serve customers. Our merchandisers and pharmacy drug hub experts can maximize your success as a business owner. Whether its guidance on setting up the front end or information on new offerings and products, our customers regularly share feedback on what a difference our team has made to their store.

Another limitation is pointed out in the paper that multiple online suppliers might belong to the same vendor. This problem might be addressed by studying the product overlapping patterns over time to merge suppliers, which might reveal more interesting hierarchical clustering patterns. Another important source of information is the trading cash flow, which is recorded in the block chain and might contribute to a comprehensive view of the supply-demand relationship. We did not include such analyses due to the time and scope constraints, and it is a topic that we plan to investigate further. In our study, we found that 23.78% (9896/41,614) listings and traces were identified with the help of 58 opioid jargons (Table 2).

Manufacturers participating in Medicaid agree to provide outpatient drugs to covered entities at significantly reduced prices. The National Maternal Mental Health Hotline provides free, confidential mental health support. Novartis broke ground on a 700,000-square-foot flagship manufacturing hub in December. Slated to open in by 2028, the project includes a new facility in Morrisville and a new site in Durham, as well as expansion of an existing Novartis facility in Durham. In Greece, the souvlatzidiko (souvlaki shop) is far more than a fast food joint; it is a cornerstone of daily social life and a true cultural landmark.

HUB Organoids (HUB) is the global leader in the field of adult stem cell-derived organoids. HUB Organoid Technology represents a paradigm shift for drug discovery and development, preclinical patient stratification, predictive diagnostics, personalized medicine, clinical trials, regenerative medicine, and companion diagnostics. HUB offers licenses to its proprietary technology and provides drug development services using its living organoid biobanks.

Top priorities include expanding its strong quality culture across the organization to ensure a harmonized, global system, and nurturing the build-out of its new Bio Campus in Songdo, South Korea. If found guilty of these charges, Wilson faces a maximum penalty under federal law of life imprisonment, followed by a term of supervised release. The final sentence will be determined by a judge, taking into consideration applicable federal sentencing statutes and the Federal Sentencing Guidelines. It is important to note that indictments are formal accusations, and all individuals charged are presumed innocent until proven guilty in a court of law. The investigation into these alleged activities was a collaborative effort between the Federal Bureau of Investigation (FBI) and the Pennsylvania State Police. Assistant United States Attorney Scott Ford is overseeing the prosecution of this case.